sperm (Total 1732 Patents Found)

Sperm (1732 Patents Found)
Nucleic acid and protein sequences relating to a cation channel which is sperm-specific (CatSper4) are disclosed. The CatSper4 protein is shown to be specifically expressed in sperm. Nucleic acids, vectors, transformed cells, transgenic animals, polypeptides, and antibodies relating to the CatSper4 gene and protein are...
This invention describes unique patterns of distribution of ganglioside G M1 in non-capacitated sperm and demonstrates that the pattern of distribution of G M1 undergoes changes that can be correlated with the process of capacitation and/or with acrosomal exocytosis. Accordingly, the present invention discloses a met...
The invention relates to methods of increasing the genetic progress of a line, breed or herd of swine through the use of sex-selected sperm cells in artificial insemination techniques. The invention also encompasses methods of artificially inseminating a swine via deep intrauterine catheter or via a laparoscopic proced...
Il est possible d'utiliser comme contraceptif une glycoprotéine humaine et ses oligosaccharides. Les oligosacharides conjugués à d'autres polymères et substances peuvent servir dans des méthodes diagnostiques et thérapeutiques relatives à la stérilité....
<P>PROBLEM TO BE SOLVED: To provide a sperm motility weakening type contraceptive liquid injector pack made by filling "contraceptive liquid" and reducing an amount of the "contraceptive liquid" to reduce power of sperms to reach the fallopian tube via the uterus by weakening sperm motility, even ...
The invention concerns methods and kits for evaluating the semen quality. The invention also concerns compounds and compositions for preserving a sperm sample, especially during cryopreservation. The invention is based on a correlation between sperm phosphodiesterase (PDE) activity and sperm fertility and on the use of...
A method of analyzing particles in a fluid stream including focusing a generally elliptical beam spot to a width less than the size of the particles. As particles pass through the beam spot electromagnetic radiation from the particles which is then detected and converted into electrical signals indicative of characteri...
The present invention relates to a macromolecule of proteinaceous nature which activates sperm motility, a process for the preparation thereof by purification of the macromolecule from extracellular fluids, pharmaceutical preparations containing the macromolecule and antibodies directed against determinants specific to...
The invention relates to a sperm dilution medium that comprises a base medium to which are added yolk or yolk plasma, glycerol and native phosphocaseinate. The medium can particularly be used for the freeze-preservation of mammal sperm in order to enhance the fertilization capability of the frozen sperm....
In various aspects, the present invention provides novel and effective methods and kits for the isolation of sperm and sperm DNA from samples having at least one other cell type, or having the DNA of one other cell type. More specifically, a process for isolating sperm DNA from a mixture of sperm and non-sperm cells by...
The present invention relates to a macromolecule of proteinaceous nature which activates sperm motility, a process for the preparation thereof by purification of the macromolecule from extracellular fluids, pharmaceutical preparations containing the macromolecule and antibodies directed against determinants specific to...
This disclosure provides a method for determining if a patient is likely to, or not likely to, experience ovarian cancer utilizing SP17 as a biomarker. It also provides methods and therapies to treat patients identified as at risk for ovarian cancer or alternatively, as identified as having a poorer prognosis....
A method and system for sorting sperm samples according to different levels of DNA fragmentation and methods of using populations with low levels of DNA fragmentation to improve fertility and success rates of assisted reproductive procedures, including artificial insemination, in vitro fertilization, intracytoplasmic i...
The perinuclear theca 32 (PT32) protein is disclosed and shown to interact with tyrosine kinase c-Yes. PT32, c-Yes, fragments thereof, and molecules that bind thereto can be used in methods of enhancing fertility, treating or diagnosing diminished fertility and abnormal spermiogenesis, in providing contraception, and i...
An injector for injecting a fertilized ovum(ova) or a sperm(s) for artificial insemination into a uterine body, by which an injection pipe can be introduced smoothly into a uterus, is disclosed. An injector for a fertilized ovum(ova) or a sperm(s) of the invention is characterized in that it comprises a guide pipe for ...
A method for the simultaneous determination of the total concentration of sperm cells and the proportion of live sperm cells in a semen sample is provided. By selective staining of live, dead and/or dying sperm cells, for example using one or more fluorochromes, the detection means can distinguish between live, dead an...
Ancestry has a significant impact on the major and minor alleles found in each nucleotide position within the genome. Due to mechanisms of inheritance, ancestral-specific information contained within the genome is conserved within members of an ancestry. For this reason, individuals within a specific ancestry are more ...
A composition and method is provided to modify sperm fertility and sex ratio of mammalian offspring. The composition includes an amount of a class of compounds of phenoxazine or phenothiazine, having the structure (see FIG. 1 ) and ionic derivatives thereof, wherein R1 is H, a lower alkyl group or N(R3)2, R2 is N, S, ...
Disclosed is a synthetic peptide, useful as an immunocontraceptive agent and for the diagnosis of autoimmune infertility, which corresponds to an autoantigenic epitope of Rabbit Sperm Membrane Autoantigen (RSA). The synthetic peptide is selected from the group consisting of the decapeptide NH 2 -pro-gly-gly-gly-thr-le...
Provided are compositions and methods for determining or diagnosing abnormal sperm or fertility, comprising: obtaining sperm DNA from a test subject; determining the methylation status of at least one CpG dinucleotide sequence of at least one gene sequence selected from HRAS, NTF3, MT1A, PAX8, DIRAS3, PLAGL1, SFN, SAT2...
The invention belongs to the field of biotechnology and medicine science, and provides sperm binding protein HEL-127 specifically expressed in human epididymis and a nucleic acid sequence for coding the protein. The invention also discloses a preparation method and application of the protein HEL-127. The protein is ass...
This invention provides isolated nucleic acid encoding sperm-specific protein kinase A anchoring proteins from mammalian species, recombinant expression constructs encoding said mammalian sperm-specific protein kinase A anchoring proteins, cells transformed with said constructs, and homogenous preparations of these pro...
A process and system for selecting mature sperm for assisted reproduction techniques such as intracytoplasmic sperm injection comprises applying a binding substrate specific to mature sperm to a surface; applying a sperm suspension to the surface; and contacting the sperm suspension and the mature sperm binding substra...
The present invention discloses a sperm selecting system and the method thereof. The brief concept of the present invention is to generate a flow field by hydraulic pressure difference then utilize the property that the sperm swims against the flow field so as to difference the sperms by vitality thereof. One of the ma...