compounds (Total 227094 Patents Found)

Novel heterocyclic compounds shown by the formula ##STR1## wherein Het represents a 5-membered or 6-membered heterocyclic group which may have substituent(s); Z represents a sulfur atom or oxygen atom; X represents an oxygen atom or the unsubstituted or substituted imino group shown by N--R 1 (wherein R 1 is a hydrog...
Supported catalysts comprised of one or more metals of Group VIII, optionally one or more metals from Group IB and IIA, aluminum and silicate are used for hydrogenating hydrogenatable organic compounds. The catalysts can be produced by coprecipitating metal ions from Group VIII, optionally metal ions from Groups IB and...
Metal-free azo compounds of the formula ##STR1## wherein Ra is an aromatic group or an active methylene coupling component radical as defined in the specification, R t is an arylazo group or a group of the formula --Y--Z, wherein Y is a direct bond or a bridging radical, and Z is a basic amino or qua...
A method is described for the covalent attachment of linker groups to specific sites on antibody molecules directed against any desired target antigen (tumor, bacterial, fungal, viral, parasitic etc.). These linkers can be attached via amide or ester bonds to compounds for delivery which contain available amino or hydr...
A process for preparing a compound of formula (I) ##STR1## (where (i) R 1 is an ethoxy group and R 2 is a hydrogen atom, (ii) R 1 is a hydrogen atom and R 2 is a bromine atom or (iii) (R 1 and R 2 together with the carbon atom to which they are attached represent>C═O) which comprises stereoselectively reduci...
1-(4-Hydroxy-3,5-di-tert.-butylbenzoyl)homopiperazine and various derivatives thereof substituted on the nitrogen are prepared starting from 4-hydroxy-3,5-di-tert.-butylbenzoic acid or its derivatives and homopiperazine or appropriate derivatives thereof. The compounds and their physiologically tolerated acid add...
Unsubstituted or substituted halo nitro and nitroso compounds and their metabolites are potent, selective and non-toxic inhibitors and supressants of cancer growth and viral infections in a mammalian host. The compounds are particularly useful for treatment and supression of tumors and viruses associated with breast ca...
Derivatives of C-076 are described in which the C-076 molecule, as series of macrolides, has a specific unsaturation, at the 22,23-position, catalytically reduced. Further reaction of the reduced C-076 compounds are also possible. The compounds thus produced have profound anthelmintic, insecticidal, ectoparasiticidal a...
A method for regeneration of catalyst which comprises phosphorus and alkali metal element and/or alkaline earth metal element and was deteriorated by use to produce aziridine compound represented by the general formula ##STR1## wherein R is hydrogen, a methyl group or an ethyl group, by a catalytic vapor-phase intramol...
Compounds of the general formula VI-1 and processes for their preparation: wherein t, u, v and w each independently represent a nitrogen atom or a methine group which may have a substituent selected from the group consisting of halogen, lower alkyl, lower alkoxy and optionally protected...
A technique is described for the preparation of a wide variety of basic derivatives of linearly condensed tricyclic systems formed by two external benzene nuclei and a 7-membered central ring having 2 chalcogen atoms as hetero atoms. Derivatives of 11H-dibenzo(b,e)-1,4-dioxepin are obtained when the chalcogens ar...
Chloroalkylthiolcarbamate compounds of the formula: ##STR1## wherein Z represents ##STR2## and when Z is ##STR3## n is an integer of 4 to 10, whereas when Z is ##STR4## n is an integer of 3 to 10. These compounds are useful as effective herbicides having no harmful effect on the ecosystem, particularly extremely low to...
A process for the preparation of carbonyl compounds by oxidation of alcohols in the gas phase with a gas containing oxygen in the presence of catalysts containing copper or silver and a phosphorus compound that is volatile under the conditions of the reaction, the ratio of the mass of phosphorus to the mass of the alco...
Compounds of the formula I ##STR1## having the meanings of the substituents indicated in the claims are outstandingly active substances for the production of medicaments for the prophylaxis and for the therapy of cardiovascular disorders, in particular arrhythmias, for the treatment of ulcers of the gastro-intestinal r...
Water-soluble polyacetylenic alkali metal salts from monomers and polymers of carboxymethyl urethanes of di-, tetra-, and hexayne diols, or from the corresponding diacids; useful in thermal and irradiation exposure indicators and/or in detection and/or removal of nonalkali metal ions dissolved in aqueous media....
A compound of the formula (I) is provided ##STR1## wherein A represents a group of the formula: ##STR2## R 1 and R 2 are independently hydrogen, halogen or a group of the formula --OR 9 ; R 9 is hydrogen, alkyl, alkylsulfonyl, haloalkylsulfonyl, arylsulfonyl or a hydroxy-protecting group; R 3 and R 4 are independ...
Highly hydrophilic indole and benzoindole derivatives that absorb and fluoresce in the visible region of light are disclosed. These compounds are useful for physiological and organ function monitoring. Particularly, the molecules of the invention are useful for optical diagnosis of renal and cardiac diseases and for es...
A method for preparing 1α-hydroxyvitamin D compounds from 1α-hydroxy-3,5-cyclovitamin D compounds which comprises solvolyzing the 3,5-cyclovitamin D compound, exposing the solvolysis reaction products to actinic radiation in the presence of a photosensitizing agent and recovering the 1α-hydroxylated vitamin D compou...