Benzofuran-2-yl-imidazole mit pharmazeutischer Wirkung, ihre Salze und relevante Verfahren zu ihrer Herstellung

(Benzofuran-2-yl)imidazoles having pharmaceutical activity, their salts and relevant production processes

Benzofuran-2-yl-imidazoles avec activité pharmaceutique, leurs sels et procédés relatifs pour leur préparation


Compounds corresponding to the general formula I wherein: - R and R1, that may be different, represent a hydrogen atom, a halogen, an alkyl group, an alkoxy radical in which the alkyl group contains one to four carbon atoms, a nitro group, a cyano group, an amino group, an acetamino group, a sulfamidic or N-substituted sulfamidic group; R2 represents a hydrogen atom, a halogen, an alkoxy radical, an alkyl group, a phenyl group, a phenylalkyl group, in which the alkylen radical contains two to four carbon atoms, a nitro group, a cyano group, an amino group, an acetamino group, an N-substituted sulfamidic group; and R3 represents a hydrogen atom, an alkyl group, preferably containing one to three carbon atoms or a cyano group, are useful as antifungal and antibacterial agents.




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    EP-0574992-A1December 22, 1993Glaxo Group LimitedDérivés de 5(1,2,4-triazol-1-ylméthyl)-3H-isobenzofuran-1-one, leurs préparation et application en tant qu'inhibiteurs d'aromatase
    US-5426196-AJune 20, 1995Glaxo Inc.Synthesis of diaryl methanes
    US-5578630-ANovember 26, 1996Glaxo Group LimitedHeterocyclic compounds which inhibit aromatase
    US-6503935-B1January 07, 2003Abbott LaboratoriesImidazoles and related compounds as α1A agonists
    WO-2004035568-A1April 29, 2004University College Cardiff Consultants LimitedDerives de benzofurane, formulations et leurs utilisations
    WO-9325548-A1December 23, 1993Glaxo Group LimitedDerives de 5-(1,2,4-triazol-1-ylmethyl)-3h-isobenzofuran-1-one, leur preparation et leur utilisation comme inhibiteurs d'aromatase
    WO-9818791-A1May 07, 1998A. Menarini Industrie Farmaceutiche Riunite S.R.L.Composes de furane heterocycliques, preparation de ces composes et utilisation de ces composes comme inhibiteurs d'aromatase